From: Mubix’s Links

Script to force people to unfollow you on twitter – Python

I left the authenticity token and Cookie partially filled out so you know what to look for in your request. But basically you fill out those two variables, plus your user / pass of course and it will go through 100 pages of your followers, which should peg out your API calls. You’ll have to wait another hour to keep going, but you could easily put this on a loop until it you got down to 0. The out put could use a bit of cleaning up. You’ll need python-twitter, but BT4 and Ubuntu at least has it in it in their repos for easy install.

#!/usr/bin/python

import twitter
import urllib2

headers = {
'User-Agent' : "Mozilla/5.0 (Windows; U; Windows NT 5.1; en-US; rv:1.9.1.3) Gecko/20090824 Firefox/3.5.3 (.NET CLR 3.5.30729)",
'Cookie' : "__utma=",
}

data = "authenticity_token=&twttr=true"

api = twitter.Api(username='joeuser', password='password1')
for b in range(1,100):
users = api.GetFriends(page=b)
for i in users:
request = "http://twitter.com/friendships/destroy/" + str(i.id)
req = urllib2.Request(request,data,headers)
post = urllib2.urlopen(req)
print post